Benlysta (belimumab) is a prescription drug that treats lupus by reducing the number of certain proteins in your blood that attack your body. Your response to this drug may vary based on your medical history and diagnosis.

Benlysta belongs to a class of medications called monoclonal antibodies.

Benlysta works by attaching to certain autoantibodies (proteins in your blood that attack your body). The drug reduces the number of autoantibodies you have, which can help manage your lupus symptoms.

Doctors always prescribe Benlysta with other lupus treatments, such as corticosteroids or immunosuppressants.

The way a drug works is known medically as its mechanism of action.

Benlysta begins to work in your body as soon as you receive your first dose. But you may not notice changes in your lupus symptoms until you’ve had a few doses.

In studies of Benlysta, some people began to notice reduced lupus symptoms as early as 8 weeks. But it may take 6 to 12 months to see the full effects of Benlysta.

If you have questions about what to expect from your Benlysta treatment, talk with your doctor.

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